0559 GMT March 22, 2018
Allergen-specific immunotherapy, or allergy shots, involves injecting very small amounts of bee venom under a patient's skin to force the body to get accustomed to the poison and end excessive reaction, UPI wrote.
Researchers found some preparations of allergy shots contained up to three of the five allergens were present at levels that were low.
Dr. Simon Blank, research leader at the Center of Allergy and Environment, or ZAUM, that collaborated with the Helmholtz Zentrum Munchen German Research Center for Environmental Health, said, "Allergic reactions to insect venoms are potentially life-threatening and constitute one of the most severe hypersensitivity reactions.
"We now know that bee venom is a cocktail of many different substances. In particular, there are five components that are especially relevant for allergy sufferers.
“In our current investigation of commercial preparations, however, we were able to show that these so-called major allergens are not present everywhere at sufficient levels, and some allergens are seriously underrepresented."
Researchers could not state exactly what a difference in immunotherapy preparations means for overall therapeutic success.
The concern, researchers said, is whether the shots are effective when the specific bee venom allergens patients react to are possibly not at adequate levels in immunotherapy shots.
Dr. Carsten Schmidt-Weber, director and professor at ZAUM, said, "The vast majority of patients benefit from such a treatment.
"A desirable objective that results from this work, however, would be for patients to receive a customized treatment in the future.
“This would be a preparation with exactly the allergens to which the particular patient actually reacts."