0529 GMT April 26, 2018
Cryopreservation of ovarian tissue is of interest to women whose reproductive potential is threatened by cancer therapy
Embryo cryopreservation and human oocyte cryopreservation (egg freezing) can be complicated and time-consuming, therefore cryopreservation of ovarian tissue is more successful in prepubertal girls at risk for premature ovarian failure and patients suffering cancers.
Laser assisted zona pellucida hatching of frozen embryos, removal of necrotic blastomeres, using cryo straw, cryolife and cryotop in embryo and oocyte cryopreservation and applying cryopen in ovarian tissue cryopreservation are also conducted at Royan Institute.
Dr. Rouhollah Fathi, faculty member of Embryology Group at Royan Insritute, has conducted research on the field.
His paper entitled "Optimal Strategy toward Fertility Preservation: In Vivo and In Vitro Post-thaw Options in Gamete, Embryo and Ovarian Tissue Cryostorage" has been published in international journals.
Royan Institute's researchers are also conducting research on the side-effects of freezing eggs, causes of miscarriage and sperm disorders.
First ovarian transplant with cryopreserved ovarian tissue was performed by Dr Kutluk Oktay in 1999. In Sep 2004, Prof. Donnez of Louvain in Belgium reported the first successful ovarian birth from slow, or controlled rate, frozen ovarian tissue.